Early-life inflammation, such as trauma and viral infections, strongly increases the risk of depression in adulthood. However, the mechanisms are not clear yet.
Jul 15, 2021
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The prefrontal cortex (PFC) is a brain region that regulates cognitive functions, and a distinct feature of the region is protracted adolescent maturation, to acquire mature cognitive abilities in adulthood. In a new report ...
To break down toxic proteins more quickly, immune cells in the brain can join together to form networks when needed. This is shown by a joint study of the University of Bonn, the German Center for Neurodegenerative Diseases ...
Sep 22, 2021
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The chemotactic protein CCL17 attracts immune cells to where they are needed. Doctors have long known that a high level of CCL17 in the body indicates an allergic reaction. Researchers led by the University of Bonn have now ...
Sep 13, 2018
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(Medical Xpress)—In many pathologies of the nervous system, there is a common event - cells called microglia are activated from surveillant watchmen into fighters. Microglia are the immune cells of the nervous system, ...
Oct 16, 2012
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Pericytes, a little-understood type of cell on the brain's blood vessels, grow into the empty space left when neighboring pericytes die, report researchers at the Medical University of South Carolina (MUSC) in a January 2nd, ...
Jan 2, 2018
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An important part of the brain's immune system, cells called microglia constantly extend and retract "branches" from their cell body to survey their environment. Think of an octopus, not moving its body, but reaching its ...
Dec 15, 2020
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More than 50,000 bone marrow-derived stem cell transplants are performed worldwide each year to treat a wide range of conditions, including brain diseases. Before the cells are transplanted, the patients are given chemotherapy ...
Feb 21, 2022
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As a part of its life cycle, the human immunodeficiency virus-1 (HIV) inserts a copy of its DNA into human immune cells. Some of these newly infected immune cells can then transition into a dormant, latent state for a long ...
Jun 16, 2023
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A characteristic feature of Alzheimer's disease is the presence of so called amyloid plaques in the patient's brain - aggregates of misfolded proteins that clump together and damage nerve cells. Although the body has mechanisms ...
Dec 21, 2016
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