Medical research

Silver-plated gold nanostars detect early cancer biomarkers

Biomedical engineers at Duke University have engineered a method for simultaneously detecting the presence of multiple specific microRNAs in RNA extracted from tissue samples without the need for labeling or target amplification. ...

Genetics

Releasing molecular 'brake' kick-starts immune cell function

The immune system's ability to marshal specialized cells to fight off infection relies in part on tiny molecules called microRNAs, which act as a release for the "brakes" that keep cells dormant until needed, according to ...

Oncology & Cancer

Researchers study radiation resistance in brain cancer cells

In a vertical climb to avoid collision with a towering mountain, a plane ejects cargo to gain altitude. Investigators at the University of Minnesota showed that cancer cells perform similar feats in escaping the killing effects ...

Diseases, Conditions, Syndromes

Tiny RNA that should attack coronavirus diminish with age, disease

A group of tiny RNA that should attack the virus causing COVID-19 when it tries to infect the body are diminished with age and chronic health problems, a decrease that likely helps explain why older individuals and those ...

Oncology & Cancer

Novel therapeutic targets in cutaneous squamous cell carcinoma

Cutaneous squamous cell carcinoma (cuSCC) is the second most common diagnosed malignancy in the United States, with approximately 700,000 new cases each year. Cumulative exposure to ultraviolet light is the primary environmental ...

Oncology & Cancer

MicroRNA exhibit unexpected function in driving cancer

Researchers long thought that only one strand of a double-stranded microRNA can silence genes. Though recent evidence has challenged that dogma, it's unclear what the other strand does, and how the two may be involved in ...

Psychology & Psychiatry

Mechanism connects early binge drinking to adult behaviors

University of Illinois at Chicago researchers report that intermittent exposure to high levels of alcohol in adolescent animals leads to increased levels of microRNA-137—a molecule that regulates gene expression in cells—in ...

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