Oncology & Cancer
Genetic switch shuts down lung cancer tumors in mice
Yale researchers manipulated a tiny genetic switch and halted growth of aggressive lung cancer tumors in mice and even prevented tumors from forming.
Oct 25, 2012
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News tagged with microrna
Genetics
Mouse study finds aging sperm affects microRNA, increasing the risk of neurodevelopmental disorders
A recent study has reported that changes in mice sperm microRNAs brought about by aging may affect the growth and development of offspring. The finding adds to the growing literature on the effects of paternal aging on offspring.
Jan 12, 2024
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Immunology
Study shows microRNAs in immune cells help protect against metabolic defects in obesity
Vanderbilt researchers have demonstrated that a cluster of microRNAs—small pieces of RNA that regulate gene expression—work in a type of immune cells called macrophages to help protect against metabolic defects in obesity.
Sep 8, 2023
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Neuroscience
Research reveals ultra small molecule as a potential new target for Alzheimer's disease
A new study from the Netherlands Institute for Neuroscience and the VIB-KU Leuven Center for Brain and Disease Research shows that a very small molecule called microRNA-132 can have a significant impact on different brain ...
Jun 15, 2023
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Oncology & Cancer
New study suggests simple test could detect breast and ovarian cancer risk without genetic sequencing
Researchers from Dana-Farber Cancer Institute, Brigham and Women's Hospital, and Medical University of Lodz have found a way to detect increased cancer risk associated with BRCA1 and BRCA2 mutations without genetic sequencing, ...
Jun 8, 2023
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Medical research
Softening stiff hair follicle stem cells with a microRNA regrows hair
Just as people's joints can get stiff as they age and make it harder for them to move around, hair follicle stem cells also get stiff, making it harder for them to grow hair, reports a new Northwestern Medicine study.
Jun 5, 2023
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Oncology & Cancer
Researchers develop new CRISPR-based tool for cancer diagnosis
A team of University of Florida researchers has developed a promising new CRISPR-powered method for non-invasive blood tests that could help clinicians diagnose cancer at earlier stages.
May 31, 2023
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Genetics
Possible treatment strategy identified for bone marrow failure syndrome
Bone marrow is the spongy tissue inside bone responsible for making red blood cells, white blood cells and platelets. Bone marrow failure syndromes lead to an increased risk of developing dangerous infections, anemia and ...
Mar 2, 2023
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Genetics
How genetics influences our body weight beyond genes
Heredity plays a role in how strongly we are predisposed to put on excess weight. In recent years, researchers have extensively examined which genes and gene variants play a role in this, and have identified roughly one hundred ...
Oct 10, 2022
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Diseases, Conditions, Syndromes
How herpesviruses awaken
Eight different herpesviruses are known to date in humans. They all settle permanently in the body after acute infection. Under certain circumstances, they wake up from this dormant phase, multiply and attack other cells. ...
May 4, 2022
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MicroRNA
In genetics, microRNAs (miRNA) are single-stranded RNA molecules of 21-23 nucleotides in length, which regulate gene expression. miRNAs are encoded by genes from whose DNA they are transcribed but miRNAs are not translated into protein (i.e. they are non-coding RNAs); instead each primary transcript (a pri-miRNA) is processed into a short stem-loop structure called a pre-miRNA and finally into a functional miRNA. Mature miRNA molecules are partially complementary to one or more messenger RNA (mRNA) molecules, and their main function is to down-regulate gene expression. They were first described in 1993 by Lee and colleagues in the Victor Ambros lab , yet the term microRNA was only introduced in 2001 in a set of three articles in Science.
This text uses material from Wikipedia, licensed under CC BY-SA
