Psychology & Psychiatry

Molecular profiling of Ketamine's rapid antidepressant effect

One third of the patients with major depressive disorder suffer from treatment resistance and do not respond to commonly used antidepressants. Ketamine, a drug that works through a different mechanism, improves depressive ...

Genetics

Lifestyle influences metabolism via DNA methylation

An unhealthy lifestyle leaves traces in the DNA. These may have specific effects on metabolism, causing organ damage or disease. Scientists of Helmholtz Zentrum M√ľnchen have now identified 28 DNA alterations associated with ...

Oncology & Cancer

Clinical trials for cancer, one patient at a time

Columbia University Medical Center (CUMC) researchers are developing a new approach to cancer clinical trials, in which therapies are designed and tested one patient at a time. The patient's tumor is "reverse engineered" ...

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