(Medical Xpress)—In the ongoing quest to design new beneficial molecules or identify potential drugs catalogued in pharmaceutically databases, a critical requirement is determining how a ligand (typically a modulator, or ...
A spectrum of neurodegenerative diseases, including frontotemporal dementia (FTD), progressive supranuclear palsy (PSP) and corticobasal degeneration (CBD) are due to the accumulation of abnormal, misfolded tau proteins in ...
Apr 4, 2024
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Researchers at EPFL reveal how Drosophila's Turandot proteins protect against immune self-harm. The study is the first to identify some proteins that protect against antimicrobial peptides offering insights into cellular ...
Mar 26, 2024
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Alzheimer's disease (AD) is a debilitating incurable disease that affects millions of patients worldwide. Deposits of amyloid beta (Aβ) amyloid in the brain is key to AD pathology at early stages. Apolipoprotein E (apoE) ...
Dec 7, 2023
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Chimeric antigen receptors (CARs) have opened up an exciting new field of therapeutic advancements for rare and difficult-to-treat cancers, as they have the ability to deliver targeted therapies that can kill tumor cells.
Dec 1, 2023
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Researchers from the National Institutes of Natural Sciences and Nagoya City University have achieved a significant breakthrough by elucidating the structure of amyloid β (Aβ) bound to glycolipids on the surface of nerve ...
Aug 7, 2023
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Siglec-15 has emerged as a promising target for therapeutic intervention in the field of cancer treatment, primarily due to its unique expression pattern and potential as an immune modulator. Its distinct expression profile, ...
Jun 16, 2023
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Over the past two years, scientists have studied the SARS-CoV-2 virus in great detail, laying the foundation for developing COVID-19 vaccines and antiviral treatments. Now, for the first time, scientists at the Department ...
Sep 8, 2022
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Let's think for a second about thought—specifically, the physics of neurons in the brain.
Jun 20, 2022
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A drug used to treat asthma and allergies can bind to and block a crucial protein produced by the virus SARS-CoV-2, and reduce viral replication in human immune cells, according to a new study by researchers at the Indian ...
Apr 25, 2022
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