Oncology & Cancer

AI identifies cancer cells

How do cancer cells differ from healthy cells? A new machine learning algorithm called "ikarus" knows the answer, reports a team led by MDC bioinformatician Altuna Akalin in the journal Genome Biology. The AI program has ...

Neuroscience

Repurposing cancer drug to treat neuroinflammation

The repurposing of FDA-approved drugs for alternative diseases is a faster way of bringing new treatments into the clinic. Researchers at Karolinska Institutet in Sweden have repurposed a cancer drug for treatment of neuroinflammatory ...

Genetics

A subtle genetic change gives new clues about epilepsy

Sometimes, even the alteration of a single nucleotide in a gene can cause serious disease. In a young boy with epilepsy, this kind of mutation has not just affected the functioning of the protein in question—it could also ...

Immunology

How COVID-19 triggers massive inflammation

A study led by researchers at Boston Children's Hospital explains for the first time why COVID-19 causes severe inflammation in some people, leading to acute respiratory distress and multi-organ damage. Surprisingly, the ...

Diseases, Conditions, Syndromes

Respiratory tract bacterial extracts could prevent COVID-19

Researchers from the UArizona College of Medicine—Tucson found that the bacterial lysate OM-85 blocked SARS-CoV-2 infection by decreasing the ability of the coronavirus to bind to the lung cell surface receptor ACE2.

Medications

The impact of drugs on gut microbes is greater than we thought

We are one of the most medicated generations of humans to live on our planet. Cardiometabolic diseases like type 2 diabetes, obesity, and coronary artery disease continue to increase in prevalence and together constitute ...

Gastroenterology

Scientists pinpoint key trigger of Crohn's disease

A new treatment may be on the horizon for people with a major form of inflammatory bowel disease (IBD) called Crohn's disease, after a McMaster University-led study identified serotonin as a possible trigger of flare-ups. ...

Oncology & Cancer

Understanding the tricks of lymphomas

Cellular immunotherapies have so far not been very effective against non-Hodgkin's lymphoma. A team led by Armin Rehm of the MDC has discovered a possible reason. As the they describe in Cell Reports, this cancer induces ...

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