University of Cincinnati researchers have found additional ways to target the molecular processes involved in activating a certain protein complex to potentially develop new therapies for a tumor-causing disorder.
Nov 11, 2019
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31
Scientists have identified a molecular pathway that contributes to the development of pulmonary arterial hypertension (PAH), a severe, often fatal condition that has no cure.
Sep 12, 2019
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One of the most common brain cancers in children, Sonic Hedgehog (SHH) medulloblastoma, also is one of the more survivable for most kids. Unfortunately, for a subset of patients the cancer resists treatment and relapses with ...
Aug 29, 2019
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102
Researchers have long known that dozens of inherited diseases, called toxic proteinopathies, are caused by the build-up of specific misfolded proteins in cells. But, the molecular mechanisms responsible for this accumulation ...
Jul 25, 2019
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A new study provides potential new targets for treating epilepsy and new fundamental insights into the relationship between neurons and their glial "helper" cells. In eLife, scientists at MIT's Picower Institute for Learning ...
Apr 30, 2019
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Multiple new genes involved in hearing loss have been revealed in a large study of mouse mutants by researchers from the Wellcome Sanger Institute and King's College London, and colleagues. The new genes identified reveal ...
Apr 11, 2019
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A molecular pathway that's frequently mutated in many different forms of cancer becomes active when cells push parts of their membranes outward into bulging protrusions, Johns Hopkins researchers report in a new study. The ...
Dec 11, 2018
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One of the many challenges with battling alcohol addiction and other substance abuse disorders is the risk of relapse, even after progress toward recovery. Even pesky fruit flies have a hankering for alcohol, and because ...
Oct 25, 2018
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105
Human immunodeficiency virus (HIV) and acquired immunodeficiency syndrome (AIDS), which the HIV virus can cause, continue to be one of the world's greatest health problems.
Aug 20, 2018
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53
In two recent publications, Northwestern Medicine scientists and international collaborators discovered mutations that cause improper drainage and a buildup of ocular pressure leading to one form of congenital glaucoma, and ...
Jan 30, 2018
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