Medical research

A reference tissue atlas for the human kidney

A team of researchers including Jens Hansen, Rachel Sealfon, Rajastree Menon, and colleagues of the Kidney Precision Medicine Project, built on an existing specific human kidney tissue atlas relevant to health care at single-cell ...

Medical research

Muscle health depends on sugar superstructure

For many inherited diseases, such as cystic fibrosis or Huntington disease, the disease-causing genetic mutation damages or removes a protein that has an essential role in the body. This protein defect is the root cause of ...

Neuroscience

Team discovers potential new way to treat anxiety

Chemically modified inhibitors of the COX-2 enzyme relieve anxiety behaviors in mice by activating natural "endocannabinoids" without gastrointestinal side effects, Vanderbilt University scientists will report next week.

Medical research

'Optogenetics' used to control reward-seeking behavior

Using a combination of genetic engineering and laser technology, researchers at the University of North Carolina at Chapel Hill have manipulated brain wiring responsible for reward-seeking behaviors, such as drug addiction. ...

Neuroscience

Study finds enzyme in the brain is a 'metastat' for body weight

An enzyme found in the brain acts as a major regulator of body weight, Yale researchers have discovered. In a new study, they found that removing the enzyme from neurons in a part of the brain known as the hypothalamus led ...

Medical research

The role of metabolic signaling in preventing atrial fibrillation

Research from the Yale School of Medicine indicates that a protein kinase that is a master regulator of cell metabolism is critical to preventing atrial fibrillation. The research appeared April 22 in the journal JCI Insight.

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