The cerebellum is a region of the brain critical for balance, learning of motor skills and coordination of movements. In the outer layer of the cerebellum, individual 'Purkinje' cells integrate inputs from the brain stem ...
Sep 20, 2013
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Alzheimer's disease is thought to be caused by the buildup of abnormal, thread-like protein deposits in the brain, but little is known about the molecular structures of these so-called beta-amyloid fibrils. A study published ...
Sep 12, 2013
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In a new paper in Cancer Cell, a team led by Judy Lieberman, PhD, of Boston Children's Hospital's Program in Cellular and Molecular Medicine reports "triple-negative" breast cancers may be vulnerable to drugs that attack ...
Aug 12, 2013
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Hidden in the tangled, repetitious folds of DNA structures called centromeres, researchers from Harvard Medical School and the Broad Institute have discovered the hiding place of 20 million base pairs of genetic sequence, ...
Aug 8, 2013
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Scientists from Harvard Medical School and the CSIR-Centre for Cellular and Molecular Biology in Hyderabad, India, provide evidence that modern-day India is the result of recent population mixture among divergent demographic ...
Aug 8, 2013
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Researchers have achieved dynamic, atomic-scale views of a protein needed to maintain the transparency of the lens in the human eye. The work, funded in part by the National Institutes of Health, could lead to new insights ...
Aug 5, 2013
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New research reveals that the likely culprit behind Alzheimer's disease has a different molecular structure than current drugs' target—perhaps explaining why these medications produce little improvement in patients.
Jul 1, 2013
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The discovery confirms the model proposed by the team in 2008 to account for observations that could not be explained by the established model of mitochondrial function. Mitochondria are the organelles in the interior of ...
Jun 27, 2013
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Researchers at the MRC Laboratory of Molecular Biology in the United Kingdom have determined the crystal structure of Parkin, a protein found in cells that when mutated can lead to a hereditary form of Parkinson's disease. ...
May 31, 2013
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Researchers report that they have determined the precise chemical structure of the HIV capsid, a protein shell that protects the virus's genetic material and is a key to its virulence. The capsid has become an attractive ...
May 29, 2013
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