Alzheimer's disease & dementia

Discovery sheds light on why Alzheimer's meds rarely help

New research reveals that the likely culprit behind Alzheimer's disease has a different molecular structure than current drugs' target—perhaps explaining why these medications produce little improvement in patients.

Medical research

Researchers reformulate the model of mitochondrial function

The discovery confirms the model proposed by the team in 2008 to account for observations that could not be explained by the established model of mitochondrial function. Mitochondria are the organelles in the interior of ...

Parkinson's & Movement disorders

How disease mutations affect the Parkin protein

Researchers at the MRC Laboratory of Molecular Biology in the United Kingdom have determined the crystal structure of Parkin, a protein found in cells that when mutated can lead to a hereditary form of Parkinson's disease. ...

Alzheimer's disease & dementia

Study uncovers key factor in Alzheimer's progression

(Medical Xpress)—A new study from researchers at the University of Florida may have uncovered a critical factor that drives the relentless progression of Alzheimer's disease ― a discovery that could eventually slow its ...

Medical research

Peptides for the treatment of severe diseases

A new class of drugs for the treatment of severe diseases such as cancer and autoimmune diseases is developed by the start-up Bicycle Therapeutics. The company is generating bicyclic peptides that can selectively bind disease-related ...

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