Medical research

Reinvigorating the clinical drug pipeline for TB

A research team led by scientists from the Broad Institute has uncovered a novel group of chemical inhibitors that can kill the bacteria that causes tuberculosis (TB). Importantly, these chemical compounds take aim at a previously ...

Oncology & Cancer

Scientists compare methods of drug delivery to malignant tumors

A team of biologists from Sechenov First Moscow State Medical University and Lobachevsky University (Nizhny Novgorod) has analyzed available methods of targeted drug delivery to malignant tumors. Individual approaches to ...

Immunology

Venoms are sources in the search for new medicines

Animal venoms are the subject of study at the Butantan Institute in São Paulo. But in this case, the idea is not to find antidotes, but rather to use the properties of the venoms themselves to identify molecular targets ...

HIV & AIDS

Innovative way to block HIV runs into a roadblock

Taking aim at a promising molecular target can combat the spread of retroviruses that can cause blood cancer and AIDS—but at the risk of leaving the host vulnerable to infections by other viral pathogens, a new Yale study ...

Oncology & Cancer

New computational tool may speed drug discovery

A new computational tool called fABMACS is helping scientists see beyond static images of proteins to more efficiently understand how these molecules function, which could ultimately speed up the drug discovery process.

Neuroscience

Cause of cortical malformations targeted by researchers

Cortical malformations are a major cause of epileptic seizures and are a hallmark feature of many neurodevelopmental disorders. Expanding upon its recently-published model of cortical malformations, a Yale team lead by neuroscientist ...

Oncology & Cancer

Study identifies a potential therapeutic target for lung cancer

Small-cell lung cancer (SCLC) is one of the deadliest types of cancer, and it has been several decades since new treatment options have been approved for this disease. Although recent advances in cancer treatments have focused ...

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