Medical research

Tiny cellular antennae key to fat formation in muscle

Like it or not, as we age, our muscle cells are slowly exchanged, one by one, for fat cells. This process quickens when we injure a muscle, and an extreme form of this process is also seen in muscle-wasting diseases such ...

Genetics

Study reveals gene's role in male infertility

A Virginia Commonwealth University-led research team has opened a fresh direction in the field of male infertility with a new study that examines the role of a particular gene in the formation of sperm flagella, which is ...

Medical research

Scoliosis linked to disruptions in spinal fluid flow

A new study in zebrafish suggests that irregular fluid flow through the spinal column brought on by gene mutations is linked to a type of scoliosis that can affect humans during adolescence. Found in humans and zebrafish, ...

Medical research

Ciliopathies lie behind many human diseases

In recent years, cilia, microscopic, tentacle-like extensions from biological cells, have risen from relative obscurity and are now considered important to the understanding of many human afflictions. In a December BioScience ...

Medical research

New insights into the development of ciliopathies

Diseases of the sensory or motile cilia play a key role in lung diseases or diabetes. Scientists at Helmholtz Zentrum M√ľnchen have now discovered the protein Flattop. It regulates the asymmetric positioning of cilia. Malfunctions ...

Genetics

The genes behind the guardians of the airways

Dysfunctions in cilia, tiny hair-like structures that protrude from the surface of cells, are responsible for a number of human diseases. However the genes involved in making cilia have remained largely elusive. In the first ...

Neuroscience

Team discovers genetic dysfunction connected to hydrocephalus

The mysterious condition once known as "water on the brain" became just a bit less murky this week thanks to a global research group led in part by a Case Western Reserve researcher. Professor Anthony Wynshaw-Boris, MD, PhD, ...

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