Medications

Potential drug targets for ALS and FTD identified in two studies

A pair of collaborative studies led by Fen-Biao Gao, Ph.D., have identified two potential drug targets for the diseases amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). The studies, which appear in Nature ...

Medications

Repurposed drug could help patients with motor neuron disease

A drug typically used to treat enlarged prostates and high blood pressure has shown promise as a potential new therapy for motor neuron disease (MND)—also known as amyotrophic lateral sclerosis (ALS)—according to a new ...

Neuroscience

Stem cell-gene therapy shows promise in ALS safety trial

Cedars-Sinai investigators have developed an investigational therapy using support cells and a protective protein that can be delivered past the blood-brain barrier. This combined stem cell and gene therapy can potentially ...

Medications

Exploring how psychedelic drugs affect a rat's brain

Researchers at Lund University have developed a technique for simultaneously measuring electrical signals from 128 areas of the brain in awake rats. They have then used the information to measure what happens to the neurons ...

Neuroscience

How many types of neurons are there in the brain?

For decades, scientists have struggled to develop a comprehensive census of cell types in the brain. Now, in a pair of companion papers, researchers at Columbia's Mortimer B. Zuckerman Mind Brain Behavior Institute describe ...

Neuroscience

Scientists identify new drug target to treat ALS

Scientists from the Gladstone Institutes and the University of Michigan have identified a cellular mechanism that can be targeted to treat ALS. The researchers revealed that increasing levels of a certain key protein successfully ...

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