Diseases, Conditions, Syndromes

Unlocking the secrets of lung fibrosis with a new mouse model

A RIKEN-developed mouse model of an enigmatic lung disease promises to unlock new biological insights and catalyze the development of treatments for millions affected globally. The research is published in Nature Communications.

Medical research

Scientists reverse fibrosis in preclinical studies

In cell and mouse models, Mayo Clinic researchers and collaborators have identified a way to slow and reverse the process of uncontrolled internal scarring, called fibrosis.

Oncology & Cancer

Key to targeting the spread of pancreatic cancer

An international team of researchers has revealed how aggressive pancreatic cancer cells change their environment to enable easy passage to other parts of the body (or metastasis) - the main cause of pancreatic cancer related ...

Oncology & Cancer

Missing molecule hobbles cell movement

Cells missing a certain protein on their surface can't move normally, UConn researchers report in Science Signaling. The research could give insight into how cells move and repair wounds in normal tissue, as well as how cancer ...

Immunology

Researchers identify how skin ages, loses fat and immunity

Dermal fibroblasts are specialized cells deep in the skin that generate connective tissue and help the skin recover from injury. Some fibroblasts have the ability to convert into fat cells that reside under the dermis, giving ...

Cardiology

Study hints at experimental therapy for heart fibrosis

Researchers report encouraging preclinical results as they pursue elusive therapeutic strategies to repair scarred and poorly functioning heart tissues after cardiac injury—describing an experimental molecular treatment ...

Other

Exploring 3-D printing to make organs for transplants

Printing whole new organs for transplants sounds like something out of a sci-fi movie, but the real-life budding technology could one day make actual kidneys, livers, hearts and other organs for patients who desperately need ...

Medical research

Researchers succeed in programming blood forming stem cells

By transferring four genes into mouse fibroblast cells, researchers at the Icahn School of Medicine at Mount Sinai have produced cells that resemble hematopoietic stem cells, which produce millions of new blood cells in the ...

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