Researchers from the University of Michigan Rogel Cancer Center, studying the molecular landscape of over 500 patients with an aggressive form of multiple myeloma, discovered a prevalence of activated key oncogenic pathways ...
Jul 26, 2022
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In 1873, Russian doctor J. von Rusitzky coined the term "multiple myeloma" after finding eight different types of bone marrow tumors in a single patient. Nearly 150 years later, using advanced cell sequencing technology and ...
Feb 14, 2022
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Bone marrow biopsies are the gold standard for diagnosing and monitoring the progression of multiple myeloma, but these procedures are far too invasive to perform at every patient visit. Scientists from the Dana-Farber Cancer ...
Apr 27, 2018
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Although people with multiple myeloma usually respond well to treatment, the blood cancer generally keeps coming back. Following genetic changes in how the disease evolves over time will help to understand the disease and, ...
Dec 10, 2017
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Doctors have many drugs available to treat multiple myeloma, a type of blood cancer. However, there is no way to predict, by genetic markers or other means, how a patient will respond to a particular drug. This can lead to ...
Nov 20, 2017
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Doctors are reporting unprecedented success from a new cell and gene therapy for multiple myeloma, a blood cancer that's on the rise. Although it's early and the study is small—35 people—every patient responded and all ...
Jun 5, 2017
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A compound identified by Weill Cornell Medicine scientists inhibits the growth of a rare blood cancer found in people with HIV-AIDS. Their research, published May 15 in the Journal of Clinical Investigation, also demonstrates ...
May 17, 2017
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Multiple myeloma is a cancer of the plasma cells, which are white blood cells produced in bone marrow that churn out antibodies to help fight infection. When plasma cells become cancerous, they produce abnormal proteins, ...
Apr 4, 2017
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New research shows that excess weight increases the risk that a benign blood disorder will progress into multiple myeloma, a cancer of the blood.
Nov 18, 2016
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Yale Cancer Center researchers have identified what causes a third of all myelomas, a type of cancer affecting plasma cells. The findings, published Feb. 10 in the New England Journal of Medicine, could fundamentally change ...
Feb 11, 2016
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Multiple myeloma (from myelo-, bone marrow), also known as MM, myeloma, plasma cell myeloma, or as Kahler's disease (after Otto Kahler) is a cancer of the white blood cells known as plasma cells, which produce antibodies.
These plasma cells, or B cells, are part of the immune system, formed in bone marrow, and numerous in lymphatics. Myeloma is incurable, but remissions may be induced with steroids, chemotherapy, thalidomide and stem cell transplants.
There were 15,270 cases diagnosed and 11,070 deaths in the United States in 2004, and an incidence of 4/100,000 worldwide. Median survival is 50–55 months. Chromosome diagnosis can separate patients into more or less favorable prognoses.
Myeloma is part of the broad group of diseases called hematological malignancies.
This text uses material from Wikipedia, licensed under CC BY-SA
