Neuroscience

Testing new drugs with 'ALS-on-a-chip'

There is no cure for amyotrophic lateral sclerosis (ALS), a disease that gradually kills off the motor neurons that control muscles and is diagnosed in nearly 6,000 people per year in the United States.

Medical research

Immune cells help older muscles heal like new

Biomedical engineers at Duke University have found a critical component for growing self-healing muscle tissues from adult muscle—the immune system. The discovery in mice is expected to play an important role in studying ...

Medical research

Researchers create skeletal muscle from stem cells

UCLA scientists have developed a new strategy to efficiently isolate, mature and transplant skeletal muscle cells created from human pluripotent stem cells, which can produce all cell types of the body. The findings are a ...

Medical research

Exercise may have different effects in the morning and evening

Researchers from the University of Copenhagen have learned that the effect of exercise may differ depending on the time of day it is performed. In mice, they demonstrate that exercise in the morning results in an increased ...

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Muscle

Muscle (from Latin musculus, diminutive of mus "mouse") is the contractile tissue of the body and is derived from the mesodermal layer of embryonic germ cells. Muscle cells contain contractile filaments that move past each other and change the size of the cell. They are classified as skeletal, cardiac, or smooth muscles. Their function is to produce force and cause motion. Muscles can cause either locomotion of the organism itself or movement of internal organs. Cardiac and smooth muscle contraction occurs without conscious thought and is necessary for survival. Examples are the contraction of the heart and peristalsis which pushes food through the digestive system. Voluntary contraction of the skeletal muscles is used to move the body and can be finely controlled. Examples are movements of the eye, or gross movements like the quadriceps muscle of the thigh. There are two broad types of voluntary muscle fibers: slow twitch and fast twitch. Slow twitch fibers contract for long periods of time but with little force while fast twitch fibers contract quickly and powerfully but fatigue very rapidly.

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