A recent paper published in the Journal of Physiology deepened the case for the youthfulness-promoting effects of exercise on aging organisms, building on previous work done with lab mice nearing the end of their natural ...
Jan 17, 2023
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The Hidetoshi Sakurai Laboratory at CiRA has successfully reproduced the pathology of Myotonic Dystrophy type 1 (DM1) using skeletal muscle cells generated from patient-derived iPS cells and demonstrated their use for quantitative ...
Jan 12, 2023
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When we were little, our parents told us to take our vitamins so we could grow big and strong. Now, researchers from Japan find that one particular supplement may even fix a broken heart.
Jan 4, 2023
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Atherosclerosis is a long-term arterial vessel wall disease characterized by the build- up of lipid- rich and inflamed plaques. It often goes undetected, but highly inflamed plaques disrupt and form a blood clot attached ...
Jan 3, 2023
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UT Southwestern researchers have identified the molecular function of 87 inherited genetic variants that affect the risk of prostate cancer, and the majority appear to control the activity of genes located far away from the ...
Dec 27, 2022
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Vascular diseases such as atherosclerosis, pulmonary hypertension, and cardiac fibrosis are associated with a reorganization of the structure of blood vessels. Researchers led by the University of Tsukuba have demonstrated ...
Dec 22, 2022
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Using the CRISPR-Cas9 gene editing system, UT Southwestern researchers corrected mutations responsible for a common inherited heart condition called dilated cardiomyopathy (DCM) in human cells and a mouse model of the disease. ...
Dec 21, 2022
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A new research paper was published on the cover of Aging entitled "Single nuclei profiling identifies cell specific markers of skeletal muscle aging, frailty, and senescence."
Dec 16, 2022
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Myocardial infarction is an ischemic disease in which a coronary artery supplying blood to the heart muscle is stenotic or obstructed, resulting in cardiac tissue necrosis. Due to the irreversible loss of cardiomyocytes, ...
Dec 16, 2022
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Metformin, the most prescribed drug for treating diabetes mellitus, known as type 2 diabetes, requires the presence of the growth differentiation factor 15 (GDF15)—a protein whose expression increases in response to cellular ...
Dec 16, 2022
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