The Hidetoshi Sakurai Laboratory at CiRA has successfully reproduced the pathology of Myotonic Dystrophy type 1 (DM1) using skeletal muscle cells generated from patient-derived iPS cells and demonstrated their use for quantitative ...
Jan 12, 2023
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28
UT Southwestern researchers have identified the molecular function of 87 inherited genetic variants that affect the risk of prostate cancer, and the majority appear to control the activity of genes located far away from the ...
Dec 27, 2022
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54
Using the CRISPR-Cas9 gene editing system, UT Southwestern researchers corrected mutations responsible for a common inherited heart condition called dilated cardiomyopathy (DCM) in human cells and a mouse model of the disease. ...
Dec 21, 2022
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72
An inflammatory molecule called LIGHT, appears to be the cause of life-threatening airway damage in patients with severe asthma. According to the new research from scientists at La Jolla Institute for Immunology (LJI), therapeutics ...
Dec 9, 2022
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133
Researchers at the University of Southern California Alfred E. Mann Department of Biomedical Engineering have developed a "heart attack on a chip," a device that could one day serve as a testbed to develop new heart drugs ...
Dec 7, 2022
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107
Muscle stem cells, the cells in muscle fibers that generate new muscle cells after injury or exercise, lose their potency with age. But a study by researchers at Stanford Medicine shows that old mice regain the leg muscle ...
Nov 17, 2022
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48
Viruses and bacteria have a very long history. Because viruses can't reproduce without a host, they've been attacking bacteria for millions of years. Some of those bacteria eventually became mitochondria, synergistically ...
Oct 31, 2022
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154
Duchenne muscular dystrophy (DMD) is caused by a genetic mutation and affects one in every 5,000 boys born. Because the affected gene is on the X chromosome, girls are carriers of the mutant gene but develop the disease only ...
Sep 27, 2022
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982
Why does the risk of heart disease go up as we age? Known risk factors such as hypertension or high cholesterol don't explain all cases. A first-of-its-kind study from Boston Children's Hospital now shows that the cells that ...
Aug 12, 2022
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136
A new study published in the journal Science reveals a unique form of cell communication that controls muscle repair. In damaged muscle, stem cells must work together with immune cells to complete the repair process, yet ...
Aug 4, 2022
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