Cardiology

Artificial aorta can reduce patients' blood pressure

Engineers at EPFL's Center for Artificial Muscles have developed a silicone aorta that can reduce how hard patients' hearts have to pump. Their breakthrough could offer a promising alternative to heart transplants.

Medical research

Generation of three-dimensional heart organoids

Researchers from Tokyo Medical and Dental University (TMDU) use mouse embryonic stem cells to engineer three-dimensional functional heart organoids resembling the developing heart

Medical research

Using CRISPR to find muscular dystrophy treatments

CRISPR-Cas9 gene editing technology is best known for its potential role in correcting genetic diseases. But it can also be used as a tool to find genes that act as supporting players, making the disease better or worse. ...

Medical research

Tracking titin in real time

Using new high-resolution imaging techniques, MDC researchers and colleagues have tracked titin, the body's largest protein, in real time throughout its entire lifecycle. The method and results could provide new insight into ...

Medical research

Compound identified that improves heart function in rats

Heart attack survivors may think the worst is behind them. But many later develop heart failure, a progressive disease marked by shortness of breath and swelling in the legs. Symptoms can prevent patients from working, exercising—even ...

Medical research

Polarized cells give the heart its fully developed form

When it first starts to develop, the heart is a simple tube. Reporting in the journal Nature Communications, researchers at MDC have now described how it forms itself into a its characteristic S-shape and how the ventricles ...

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