Cardiology

Atherosclerosis: Induced cell death destabilizes plaques

Many chronic disorders arise from misdirected immune responses. A Ludwig-Maximilians-Universitaet (LMU) team led by Oliver Söhnlein now shows that neutrophils exacerbate atherosclerosis by inducing smooth muscle-cell death ...

Immunology

Obesity alters airway muscle function, increases asthma risk

New research suggests that obesity changes how airway muscles function, increasing the risk of developing asthma. The study is published ahead of print in the American Journal of Physiology—Lung Cellular and Molecular Physiology.

Diabetes

The skeletal muscle inflammation enigma

Exercise is associated with skeletal muscle inflammation, yet physical activity has beneficial effects on type 2 diabetes (T2D). Recent EU research has looked at the molecules that result in this contradiction.

Medical research

Intensive care patients' muscles unable to use fats for energy

The muscles of people in intensive care are less able to use fats for energy, contributing to extensive loss of muscle mass, finds a new study co-led by UCL, King's College London and Guy's and St Thomas' NHS Foundation Trust.

Inflammatory disorders

Chronic inflammation causes loss of muscle mass during aging

People start losing muscle mass at the age of 40—about some 10 percent of the total muscle mass for each 10-year period, which may lead to fall-related injuries, slowing metabolism and reduced quality of life. Today, very ...

Medical research

Muscle paralysis may increase bone loss

Muscle paralysis rapidly causes inflammation in nearby bone marrow, which may promote the formation of large cells that break down bone, a new study finds. The article is published in the American Journal of Physiology—Cell ...

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