A team of researchers led by Associate Professor Makoto Ikeya (Department of Clinical Application) has observed early signs of success from providing iPSC-derived mesenchymal stem/stromal cells (iMSCs) instructions to produce ...
Mar 27, 2024
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The cells of a subset of myeloproliferative neoplasms (MPNs), slow-growing blood cancers, have frameshift mutations in their calreticulin (CALR) gene that are associated with the disease. The tail end of this gene's mutated ...
Sep 20, 2022
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Blocking the mutant protein with an antibody didn't stop the strange, abnormal bone growths in mice. But the knowledge gained could steer scientists toward more promising approaches, report researchers from UConn and Alexion ...
Jun 17, 2022
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A team of researchers led by Dr. Sandra Castillo and Dr. Mariona Graupera, from the Josep Carreras Leukaemia Research Institute and CIBERONC, have found the AKT inhibitor miransertib could be a new, effective molecular treatment ...
Jun 14, 2022
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Researchers at SAHMRI and the University of Adelaide have pinpointed a tumor support signal that works to suppress the immune system. Blocking this signal may prove pivotal in stopping bowel cancer.
Dec 8, 2021
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Researchers from the Brain Research Institute, Niigata University, Japan may have unraveled a new approach that could revolutionize the treatment, prevention, and possibly reversal of the damage that could lead to Parkinson's ...
Jun 10, 2021
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Humans are born with tens of thousands of hematopoietic stem cells (HSCs) that collectively ensure lifelong production of blood and immune cells that protect us from infections. HSCs can either duplicate to produce more stem ...
Mar 25, 2021
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As March comes around, many people experience hay fever. As excessive immune responses go, most would admit that hay fever really isn't that bad. At the other end of the spectrum are severely debilitating autoimmune diseases ...
Feb 17, 2021
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Researchers from Karolinska Institutet and Gothenburg University have investigated a potential new drug target for the rare genetic disorder Hutchinson-Gilford progeria syndrome that causes accelerated aging in children. ...
Feb 2, 2021
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Microglia—the brain's immune cells—play a primary role in removing cellular debris from the brain. According to a recent study by a Nagoya University-led research team in Japan, another kind of brain cell, called astrocyte, ...
Nov 9, 2020
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