Scientists have unraveled how mutant molecules damage the nervous system of people with Charcot-Marie-Tooth (CMT) disease, a group of disorders that hinder people's ability to move and feel sensation in their hands and feet, ...
Oct 21, 2015
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(Medical Xpress)—An international team of researchers working at the Washington University School of Medicine in Missouri has identified several genes associated with specific metabolic pathways in a mammal biome, including ...
Researchers have determined how the most common gene mutation in amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) disrupts normal cell function, providing insight likely to advance efforts to develop ...
Aug 26, 2015
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A gene mutation has been found to contribute to non-alcoholic fatty liver disease (NAFLD), a form of liver disease closely linked to obesity, in normal weight subjects. Carriers of the PNPLA3 mutant genotype were found to ...
Jul 22, 2015
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Huntington's disease is caused by a mutation in the Huntington's disease gene, but it has long been a mystery why some people with the exact same mutation get the disease more severely and earlier than others. A closer look ...
May 4, 2015
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Herceptin has been touted as a wonder drug for women with HER2-positive breast cancer, an aggressive form of the disease that is fueled by excess production of the HER2 protein. However, not all of these patients respond ...
Apr 28, 2015
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Complex brain disorders, such as autism or schizophrenia, still puzzle scientists because their causes lie hidden in early events of brain development, which are still poorly understood. This is about to change thanks to ...
Apr 1, 2015
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Research to understand why hereditary cancers develop resistance to a powerful cancer drug has identified an important new pathway key to chemoresistance in BRCA2-mutant cancers. The research, published in the current issue ...
Mar 5, 2015
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Up to 8 percent of people from India, Pakistan, Bangladesh and other South Asian countries carry a mutated gene that causes heart failure and potentially fatal heart attacks.
Jan 15, 2015
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Sildenafil, the active ingredient in the erectile dysfunction drug Viagra, could cause unusual visual responses in people who carry a common mutation for eye disease and may have long-term detrimental effects on their vision, ...
Sep 30, 2014
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