A gene mutation has been found to contribute to non-alcoholic fatty liver disease (NAFLD), a form of liver disease closely linked to obesity, in normal weight subjects. Carriers of the PNPLA3 mutant genotype were found to ...
Jul 22, 2015
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Huntington's disease is caused by a mutation in the Huntington's disease gene, but it has long been a mystery why some people with the exact same mutation get the disease more severely and earlier than others. A closer look ...
May 4, 2015
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Herceptin has been touted as a wonder drug for women with HER2-positive breast cancer, an aggressive form of the disease that is fueled by excess production of the HER2 protein. However, not all of these patients respond ...
Apr 28, 2015
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Research to understand why hereditary cancers develop resistance to a powerful cancer drug has identified an important new pathway key to chemoresistance in BRCA2-mutant cancers. The research, published in the current issue ...
Mar 5, 2015
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Up to 8 percent of people from India, Pakistan, Bangladesh and other South Asian countries carry a mutated gene that causes heart failure and potentially fatal heart attacks.
Jan 15, 2015
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Sildenafil, the active ingredient in the erectile dysfunction drug Viagra, could cause unusual visual responses in people who carry a common mutation for eye disease and may have long-term detrimental effects on their vision, ...
Sep 30, 2014
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Genetic risk is the contribution our genes play in the chance we have of developing certain illnesses or diseases. Genes are not the only deciding factor for whether or not we will develop certain diseases and their influence ...
May 7, 2014
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Denis Keegan was out of answers. The 30-year-old was suffering from kidney disease, but his doctors were struggling to pinpoint the cause. That's when Keegan turned to genetic testing.
Jan 28, 2014
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Researchers at A*STAR's Singapore Immunology Network (SIgN) have discovered a new mechanism involving p53, the famous tumour suppressor, to fight against aggressive cancers. This strategy works by sabotaging the ability of ...
Sep 18, 2013
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An assay designed to measure normal and abnormal forms of the huntingtin protein – the mutated form of which causes Huntington's disease (HD) – was successful in detecting levels of the mutant protein in a large multicenter ...
Aug 29, 2013
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