High-grade serious ovarian carcinoma (HGSOC) is the fifth-leading cause of cancer-related deaths in women in the United States, yet little is known about the origins of this disease.
Sep 11, 2020
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367
The Human Molecular Genetics laboratory of the de Duve Institute (UCLouvain), headed by Professor Miikka Vikkula, recently identified mutations in a novel gene, ANGPT2, responsible for primary lymphedema. Together with the ...
Sep 10, 2020
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320
The KRAS oncogene is involved in at least one fifth of all human cancers: KRAS mutations are directly responsible for 32% of lung tumors and 96% of pancreatic tumors. However, after more than thirty years of research to date, ...
Sep 09, 2020
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3
A targeted therapy called capmatinib can provide significant benefits to patients who have advanced lung cancer with specific gene mutations, according to recently published results from a phase two clinical trial. The trial, ...
Sep 08, 2020
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Within cells, molecules known as transfer RNAs, or "tRNAs," play an important but unglamorous workhorse role in keeping the genetic translation process moving along from codes of DNA to functional proteins.
Aug 26, 2020
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93
Joint research, led by Kumamoto University in Japan, has successfully reproduced the pathogenesis of autosomal dominant polycystic kidney disease (ADPKD) from human iPS cells in vitro. ADPKD is a disease that causes multiple ...
Aug 21, 2020
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Life can change dramatically when someone learns they are genetically predisposed to a disease, such as a condition called familial hypercholesterolemia, where a mutated gene can lead to elevated cholesterol and increased ...
Aug 20, 2020
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138
Analysis of the genomes of 28,000 tumors from 66 types of cancer has led to the identification of 568 cancer driver genes
Aug 17, 2020
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310
Progress against DIPG, a fatal childhood brain tumor, is usually a game of inches. Studies that hint at even small gains are cause for celebration.
Aug 13, 2020
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1321
Columbia researchers have uncovered an array of new genes that cause stillbirth, significantly increasing the understanding of the condition's genetic foundations. The findings suggest that genetic analysis could be used ...
Aug 13, 2020
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