Myotonic dystrophy 2 (DM2) is a form of muscular dystrophy, a disease that leads to progressive muscle degeneration. It is caused by the expansion of a repetitive DNA sequence containing multiple CCTG bases in the CNBP gene. ...
Feb 21, 2024
0
17
Living organisms have a knack for persisting in the face of challenges. For instance, when genes malfunction, organisms may be able to compensate by activating redundant genes with similar functions, called paralogs.
Feb 21, 2023
0
54
Scientists at the University of Nottingham have taken a step closer towards developing a treatment for the long-term genetic disorder, myotonic dystrophy.
Apr 29, 2020
0
46
Roughly 80% of people with myotonic dystrophy—a common form of muscular dystrophy—experience dangerous heart ailments, and heart rhythm defects are the second-leading cause of death in those with the condition. In a new ...
Feb 27, 2020
0
88
Disruption of a transcription network controlled by MEF2 in heart tissue of people with myotonic dystrophy type 1 – an inherited form of muscular dystrophy with symptoms starting in early adulthood – affects activity ...
Jan 9, 2014
0
0
Scientists from the Florida campus of The Scripps Research Institute have revealed an atomic-level view of a genetic defect that causes a form of muscular dystrophy, myotonic dystrophy type 2, and have used this information ...
Jan 2, 2014
0
0
Antisense oligonucleotides – short segments of genetic material designed to target specific areas of a gene or chromosome – that activated an enzyme to "chew up" toxic RNA (ribonucleic acid) could point the way ...
Feb 27, 2012
0
0
New research has identified the specific biological mechanism behind the muscle dysfunction found in myotonic dystrophy type 1 (DM1) and further shows that calcium channel blockers can reverse these symptoms in animal models ...
Jan 2, 2024
0
0
People with myotonic dystrophy experience progressive muscle weakness and repeated episodes of painless muscle stiffness called myotonia.
Apr 13, 2023
0
14
People with the inherited disorder myotonic dystrophy (DM) often experience excessive daytime sleepiness and fatigue, as well as altered responses to anesthetics that can put them at risk for complications when hospitalized.
Sep 29, 2022
0
16
