Even though most viruses cause infection directly through mucosal cells, the vast majority of vaccines are administered intramuscularly in a cellular mismatch that doesn't always produce optimum immunity.
(Medical Xpress)—The blood-brain barrier (BBB) prevents most large or hydrophilic (polar) molecules from getting into the brain. For many neurological diseases, like Parkinson's, the presence of the BBB severely limits ...
Coronaviruses spread primarily through the air. When infected people speak, cough, sneeze or laugh, they expel droplets of saliva containing the virus. Other people then breathe in these airborne pathogens and become infected ...
Apr 3, 2023
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A new study led by Gonçalo Bernardes, group leader at the Instituto de Medicina Molecular João Lobo Antunes (iMM; Portugal) and Professor at the University of Cambridge (Cambridge, UK), published recently in the journal ...
Jan 20, 2023
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A common symptom of COVID-19 is a partial or complete loss of smell. The virus infects sustentacular cells in the olfactory epithelium and is thought to impair thereby the activity of the sensory neurons in this epithelium.
Dec 8, 2022
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Scientists have shed new light on early events in the battle between COVID-19 and the immune system in the nose, a key entry point for the virus.
Dec 7, 2021
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The coronavirus SARS-CoV-2 is known to infect cells via the receptor ACE2. An international research team under German-Finnish coordination has now identified neuropilin-1 as a factor that can facilitate SARS-CoV-2 entry ...
Oct 20, 2020
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Why are severe courses of SARS-CoV-2 infection much less common in children and adolescents than in adults? Scientists at the German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ) have now discovered that ...
Oct 18, 2023
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Respiratory viruses are known for their ability to enter the body through the eyes, nose, or mouth. Our bodies know that too. The nasal cavity is well-equipped with sticky mucus that traps pathogens and serves as an important ...
Jun 27, 2023
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Vaccines that provide long-lasting protection against influenza, coronaviruses and respiratory syncytial virus (RSV) have proved exceptionally difficult to develop. In a new review article in Cell Host & Microbe, researchers ...
Jan 11, 2023
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