Researchers and data scientists at UT Southwestern Medical Center and MD Anderson Cancer Center have developed an artificial intelligence technique that can identify which cell surface peptides produced by cancer cells called ...
Sep 23, 2021
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Vaccination with as few as four tumor antigens generated antigen-specific responses, reduced intestinal tumors, and improved survival in a mouse model of Lynch syndrome, suggesting that it may be possible to develop a cancer ...
Apr 1, 2019
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A Ludwig Cancer Research study has devised a highly efficient method to generate large numbers of immune cells specifically engineered to recognize neoantigens—small fragments of randomly mutated proteins that are typically ...
Nov 15, 2021
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Neoantigens, tiny markers that arise from cancer mutations, flag cells as cancerous and could be the key to unlocking a new generation of immunotherapies. Targeting the "right" neoantigens—in a cancer vaccine or a cell ...
Oct 9, 2020
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Advanced bowel cancer cells have very few "molecular flags" on their surface, helping to explain why they may be hard for the immune system to detect, a new study has shown.
Nov 18, 2019
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Researchers at the Icahn School of Medicine at Mount Sinai have discovered a way to move precision immunotherapy forward by using genomics to inform immunotherapy for multiple myeloma, a blood cancer, according to a study ...
Dec 19, 2019
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An innovative computational tool dubbed "SNAF" may help the research world bring the emerging promise of cancer immunotherapy to a wider range of patients, according to a study published in Science Translational Medicine. ...
Jan 17, 2024
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Wistar scientists and collaborators demonstrated the utility of an optimized synthetic DNA vaccine platform for rapidly inducing immunity against unique combinations of tumor neoantigens. These results reveal a direct pathway ...
Jan 24, 2019
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Researchers at the Cheriton School of Computer Science have applied machine learning to identify tumor-specific antigens, which could help make personalized cancer vaccines practically feasible and more accurate.
Apr 30, 2021
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