Some infants are born with too few nephrons, the filtering units in kidneys that help the body remove waste and excess fluid. Whether due to low birth weight, maternal diabetes, inadequate nutrition or genetic mutations, ...
Mar 15, 2024
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Proper function of the kidney is critical for concentrating urine, regulating blood pressure, and for the tight control of electrolyte levels in the blood. The kidney achieves these important functions through many microscopic ...
Apr 25, 2022
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Besides being underweight, babies born to women whose diet lacked sufficient protein during pregnancy tend to have kidney problems resulting from alterations that occurred while their organs were forming during the embryonic ...
May 5, 2021
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More than 3,000 donated kidneys are discarded every year in the U.S., even as thousands of people die on kidney transplant waitlists. About a fifth of all donated kidneys—particularly those from people who are older, have ...
Jan 27, 2021
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While investigating the underlying causes of a rare skin disorder, a researcher at Massachusetts General Hospital (MGH) discovered a previously unknown mechanism in the kidneys that is important for regulating levels of magnesium ...
Jan 12, 2021
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Arriving early or late can have big consequences for early-stage cells that gather to form a new kidney, a team of USC researchers discovered.
Jun 4, 2018
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Nephrons are the microscopic blood-filtering units inside our kidneys that convert waste products into urine, regulate our electrolyte levels and our blood pressure.
May 21, 2018
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In the embryonic kidney, three types of precursor cells interact to form three-dimensional structures of the kidney: nephron progenitor cells, ureteric buds, and interstitial progenitor cells. Methods to induce nephron structures ...
Dec 19, 2017
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Monash University's Biomedicine Discovery Institute (BDI) scientists in Melbourne, Australia, collaborating with researchers from the Jikei University School of Medicine in Tokyo, have shown for the first time that Japanese ...
Oct 6, 2017
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Salk Institute scientists have discovered the holy grail of endless youthfulness—at least when it comes to one type of human kidney precursor cell. Previous attempts to maintain cultures of the so-called nephron progenitor ...
Aug 25, 2016
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Nephron (from Greek νεφρός - nephros, meaning "kidney") is the basic structural and functional unit of the kidney. Its chief function is to regulate the concentration of water and soluble substances like sodium salts by filtering the blood, reabsorbing what is needed and excreting the rest as urine. A nephron eliminates wastes from the body, regulates blood volume and blood pressure, controls levels of electrolytes and metabolites, and regulates blood pH. Its functions are vital to life and are regulated by the endocrine system by hormones such as antidiuretic hormone, aldosterone, and parathyroid hormone. In humans, a normal kidney contains 800,000 to 1.5 million nephrons.
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