IgA nephropathy (IgAN) is a kidney disorder characterized by the buildup of immunoglobin A (IgA) in the glomeruli, which are bundles of capillaries that filter blood in the kidney. In advanced stages of the disease, the buildup ...
Mar 22, 2023
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The kidneys perform a critical role in the body by removing waste and excess fluid in the form of urine. In a condition known as diabetic nephropathy, complications from diabetes disrupt the ability of the kidneys to function ...
Mar 7, 2023
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Increased levels of the antibody immunoglobulin A (IgA) are correlated with the manifestation of several diseases as well as African ancestry, according to findings published in Nature Communications. The findings provide ...
Jan 5, 2023
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A new Japanese study reveals that the age-standardized incidence rates of end-stage kidney disease (ESKD) requiring renal replacement therapy (RRT) due to chronic glomerulonephritis and diabetic nephropathy has decreased, ...
Dec 23, 2022
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Several reports have described a relapse of certain autoimmune kidney diseases in patients after they've received COVID-19 vaccines, but it's unclear if this association is real or a coincidence. In a recent population-level ...
Nov 3, 2022
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Some cytokines can enhance the production of aberrantly O-glycosylated IgA1, the main autoantigen in IgA nephropathy. The mechanism behind this observation is described in the Journal of Interferon & Cytokine Research (JICR).
Jul 19, 2022
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The largest ever randomized controlled trial in IgA nephropathy has found that treatment with methylprednisolone—a cheap, widely used corticosteroid drug—halves the risk of losing kidney function and kidney failure, and ...
May 17, 2022
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March is National Kidney Month, which makes this a good time to learn about diabetic kidney disease.
Mar 17, 2022
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Obesity may negatively affect kidney function in people with type 2 diabetes, particularly in women, according to a new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism.
Feb 22, 2022
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SGLT2 inhibitors (gliflozins) were developed as oral antidiabetics. They enhance urinary glucose excretion by inhibiting SGLT-2 (sodium-dependent glucose co-transporter-2) in the renal tubuli. The discovery of kidney benefits ...
Jun 7, 2021
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