Oncology & Cancer

Chimeras offer a new way to study childhood cancers in mice

In a new paper published March 5 in the journal Cell Stem Cell, researchers in Whitehead Institute Member Rudolph Jaenisch's lab introduce a new way to model human neuroblastoma tumors in mice using chimeras—in this case, ...

Oncology & Cancer

Research sheds important light on the metastasis of neuroblastoma

Neuroblastoma can grow and spread in the body very aggressively, making it very difficult to treat. New research has shed important light on the factors at play in the metastasis of neuroblastoma, which could potentially ...

Oncology & Cancer

Researchers find new way to target childhood cancer

An Australian-led international research effort has broken fresh ground in the race to find more effective treatments for the childhood cancer neuroblastoma, by uncovering a new and as-yet unexploited target in cancer cells ...

Medical research

Meet BORIS: Possible new culprit in drug-resistant cancer

Like a Russian bot corrupting U.S. elections, or a new prime minister wreaking havoc in the U.K., a protein named BORIS is showing itself to be a malevolent player in some childhood cancers. New research fingers BORIS as ...

Oncology & Cancer

Research finds new Rx target for childhood cancer

Research led by Michael Lan, Ph.D., Professor of Pediatrics and Genetics at LSU Health New Orleans School of Medicine, found that a compound named 5'-iodotubercidin (5'-IT) suppresses the growth of neuroblastoma cells and ...

Medical research

Protein BRCA1 as a stress coach

Anyone who has ever studied the molecular basis of breast cancer will probably have heard of BRCA1, a protein that protects the cells of breast tissue against cancer. Surprisingly, this protein can also have the opposite ...

page 5 from 11