Alzheimer's disease & dementia

Astrocytes as a novel target in Alzheimer's disease

Alzheimer's disease is a severe neurodegenerative disease that affects 45% of people over 85 years of age. The research teams of Prof. Jin-Moo Lee at Washington University in Saint Louis, USA, and Prof. Milos Pekny at Sahlgrenska ...

Alzheimer's disease & dementia

Researchers identify new enzyme to fight Alzheimer's disease

An enzyme that could represent a powerful new tool for combating Alzheimer's disease has been discovered by researchers at Mayo Clinic in Florida. The enzyme—known as BACE2—destroys beta-amyloid, a toxic protein fragment ...

Alzheimer's disease & dementia

Vitamin C and beta-carotene might protect against dementia

Forgetfulness, lack of orientation, cognitive decline… about 700, 000 Germans suffer from Alzheimer's disease (AD). Now researchers from the University of Ulm, among them the Epidemiologist Professor Gabriele Nagel and ...

Medical research

Detector of DNA damage: Structure of a repair factor revealed

Double-stranded breaks in cellular DNA can trigger tumorigenesis. Researchers from Ludwig-Maximilians-Universitaet (LMU) in Munich, Germany, have determined the structure of a protein involved in the repair and signaling ...

Parkinson's & Movement disorders

Researchers ID cluster of genes in blood that predict Parkinson's

Because there is currently no laboratory test that can diagnose Parkinson's disease, it is practically impossible to detect those individuals who are in the earliest stages of the disease. As a result, Parkinson's disease ...

Parkinson's & Movement disorders

Blocking LRRK2 activity is not a simple answer to Parkinson's disease

Mutations in the LRRK2 gene are the most common cause of genetic Parkinson's disease (PD). New research published in BioMed Central's open access journal Molecular Neurodegeneration demonstrates that loss of function of LRRK2 ...

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