In neuromuscular diseases, neurons and muscle cells stop communicating properly. Researchers led by Mina Gouti can now model this in 2D in a culture dish. Writing about their findings in Nature Communications, they say the ...
Dec 19, 2023
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A small molecule previously shown to enhance strength in injured or old laboratory mice does so by restoring lost connections between nerves and muscle fibers, Stanford Medicine researchers have found.
Oct 12, 2023
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Researchers at Kyushu University have uncovered the mechanisms of a fundamental yet critically under-looked phase in brain development: synaptic pruning.
Jun 7, 2023
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The neuromuscular junction—where nerves and muscle fibers meet—is an essential synapse for muscle contraction and movement. Improper function of these junctions can lead to the development of progressive neuromuscular ...
Jan 6, 2022
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A research group from the Sackler Faculty of Medicine and the Sagol School of Neuroscience at Tel Aviv University uncovered, for the first time, the biological mechanism causing nerve destruction in the neurodegenerative ...
Dec 14, 2021
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With life expectancy increasing, age-related diseases are also on the rise, including sarcopenia, the loss of muscle mass due to aging. Researchers from the University of Basel's Biozentrum have demonstrated that a well-known ...
Sep 9, 2020
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After nerve injury, the protein complex mTORC1 takes over an important function in skeletal muscle to maintain the neuromuscular junction, the synapse between the nerve and muscle fiber. Researchers at the University of Basel's ...
Jul 25, 2019
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Salk researchers have found, for the first time, that a blood-clotting protein can, unexpectedly, degrade nerves—and how nerve-supporting glial cells, including Schwann cells, provide protection. The findings, published ...
Mar 14, 2019
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Researchers at Karolinska Institutet in Sweden have discovered a new way in which nerve cells can control movement. In a study on zebrafish published in the journal PNAS they show that the contact between neurons and muscles ...
Oct 2, 2018
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Michigan State University researchers used an old-fashioned neurobiology technique to explore new avenues for treatments to reverse a late-onset neurodegenerative disease that robs men of the capacity to walk, run, chew and ...
May 6, 2016
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