Neuroscience

Biomarker for Parkinson's disease may originate in the gut

Parkinson's disease (PD) is a debilitating neurodegenerative disorder, impairing the motor functions of millions of elderly people worldwide. Often, people with PD will experience disturbances in gastrointestinal function, ...

Genetics

Gene therapy can protect against ALS and SMA-related cell death

Researchers at Karolinska Institutet in Sweden and the University of Milan in Italy have identified a gene in human neurons that protects against the degeneration of motor neurons in the deadly diseases ALS and SMA. Gene ...

Neuroscience

Disease-causing repeats help human neurons function, study finds

Over half of our genomes are made of repeating elements within DNA. In rare cases, these repeats can become unstable and grow in size. These repeat "expansions" cause neurodegenerative diseases such as ALS and dementia as ...

Neuroscience

Immunity key to motor neurone disease treatment

Customized immune-blocking medication may be the key to treating patients with motor neurone disease (MND), which currently has no cure and limited therapeutic options.

Neuroscience

Birth timing may affect brain development

Moving birth a day early triggers an early start to widespread neuron death, according to new research in mice published in eNeuro.

Medical research

Gene therapy generates new neurons to treat Huntington's disease

Huntington's disease (HD) is a rare disease characterized by abnormal chorea movement and caused by the Huntingtin (Htt) gene mutation and neurodegeneration in a brain area called the striatum. A research group led by Dr. ...