Genetics

Breakable genes may promote disease and brain cell diversity

Howard Hughes Medical Institute (HHMI) researchers have identified 27 genes in brain stem cells that are prone to a type of DNA damage. The fragility of those genes could explain why they are often mutated or deleted in cancers ...

Medical research

Stroke damage mechanism identified

Researchers have discovered a mechanism linked to the brain damage often suffered by stroke victims—and are now searching for drugs to block it.

Parkinson's & Movement disorders

Finding points to possible new Parkinson's therapy

A new study shows that, when properly manipulated, a population of support cells found in the brain called astrocytes could provide a new and promising approach to treat Parkinson's disease. These findings, which were made ...

Neuroscience

DNA damage may cause amyotrophic lateral sclerosis

Amyotrophic lateral sclerosis (ALS)—also known as Lou Gehrig's disease—is a neurodegenerative disease that destroys the neurons that control muscle movement. There is no cure for ALS, which kills most patients within ...

Medical research

Engineered stem cell advance points toward treatment for ALS

Transplantation of human stem cells in an experiment conducted at the University of Wisconsin-Madison improved survival and muscle function in rats used to model ALS, a nerve disease that destroys nerve control of muscles, ...

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