Modulating the activity of a kinase in motor neurons may help mitigate mitochondrial defects and other symptoms of spinal muscular atrophy, offering a new therapeutic avenue for the devastating disease, according to a Northwestern ...
Dec 5, 2023
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Loss of neurons in in the retina due to trauma or disease leads to vision impairment or blindness, a process which is irreversible in humans. Interestingly, some animals like fish have the built-in ability to regenerate retinal ...
Nov 30, 2023
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Pregnancy and motherhood lead to brain remodeling. A research team at the University of Basel has now discovered through experiments with mice that distinct pools of stem cells in the adult brain are turned on during pregnancy. ...
Nov 27, 2023
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Researchers at the University of Wisconsin–Madison have identified a protein key to the development of a type of brain cell believed to play a role in disorders like Alzheimer's and Parkinson's diseases and used the discovery ...
Nov 17, 2023
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A study published in Progress in Neurobiology and led by researchers at the University of Arizona College of Medicine, Tucson, has developed an improved method to study Parkinson's disease in the lab. Along the way, researchers ...
Nov 16, 2023
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The disease 5q-spinal muscular atrophy (5q-SMA) is one of the more common types of spinal muscular atrophy (SMA) affecting around 1 in 10,000 individuals worldwide. Currently, tests are unable to detect all pathogenic genetic ...
Nov 15, 2023
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In a new study, investigators at Beth Israel Deaconess Medical Center (BIDMC) have shed new light on key cellular processes involved in the progression of Parkinson's disease (PD). The research is published in the journal ...
Nov 14, 2023
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Having healthy mitochondria, the organelles that produce energy in all our cells, usually portends a long healthy life whether in humans or in C. elegans, a tiny, short-lived nematode worm often used to study the aging process.
Nov 13, 2023
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About 283 million people worldwide suffer from alcohol use disorder, a debilitating health challenge for which limited therapeutic options are available. The cost to society is estimated at greater than $2 trillion annually.
Oct 30, 2023
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Clostridioides difficile (C. diff) intestinal infections can cause severe, debilitating diarrhea in patients who are hospitalized or on immunosuppressive therapies. The infections can be very hard to eradicate, roaring back ...
Oct 26, 2023
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