On the surface, the movement disorder amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, and the cognitive disorder frontotemporal lobar degeneration (FTLD), which underlies frontotemporal dementia, ...
Mar 22, 2024
0
23
Our movements are controlled by multiple neural pathways that connect the brain and spinal cord. In particular, neurons in the cerebral cortex send commands to the motor neurons in the spinal cord and then to the muscles, ...
Aug 18, 2023
1
67
While fish, reptiles and even some birds can regenerate damaged brain, eye and spinal cord cells, mammals cannot. For the first time, non-neuronal cells have been induced to mimic specific ganglion cells in the eyes of mice.
Nov 30, 2022
0
830
Amyotrophic lateral sclerosis (ALS) is a progressive disease of the nervous system. It affects nerve cells in the brain and spinal cord called motor neurons. Motor neurons control muscle movement and ALS causes them to deteriorate ...
Jun 20, 2022
0
59
Using an experimental drug, researchers have been able to suppress a mutated amyotrophic lateral sclerosis (ALS) gene. Studies in mice demonstrate that the therapy could show promise in treating rare, aggressive forms of ...
Jan 24, 2022
0
71
Using laboratory-grown roundworms as well as human and mouse eye tissue, University of Maryland School of Medicine (UMSOM) researchers have identified a new potential mechanism for age-related macular degeneration—the leading ...
Apr 12, 2021
0
42
A newly developed light-sensing protein called the MCO1 opsin restores vision in blind mice when attached to retina bipolar cells using gene therapy. The National Eye Institute, part of the National Institutes of Health, ...
Oct 22, 2020
0
196
Scientists have long known that a protein called TDP-43 clumps together in brain cells of people with amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's Disease, and is associated with neuron death. This same ...
Jul 19, 2017
0
329
Until relatively recently, the dogma in neuroscience was that neurons, including the eye's photoreceptor cells, rods and cones, do not regenerate. This is the reason that nerve damage is thought to be so grave. More recent ...
Mar 18, 2016
0
60
A discovery into the mechanisms which lead to degeneration and loss of communication among neuron cells - the cells controlling function in the brain and nervous system - could potentially lead to future therapies for neurodegenerative ...
Dec 10, 2015
0
50
