Neuroscience

Gene therapy helps functional recovery after stroke

A new gene therapy turns glial cells—abundant support cells in the brain—into neurons, repairing damage that results from stroke and significantly improving motor function in mice. A paper describing the new therapy, ...

Neuroscience

New method classifies brain cells based on electrical signals

For decades, neuroscientists have relied on a technique for reading out electrical "spikes" of brain activity in live, behaving subjects that tells them very little about the types of cells they are monitoring. In a new study, ...

Neuroscience

Tissue model reveals role of blood-brain barrier in Alzheimer's

Beta-amyloid plaques, the protein aggregates that form in the brains of Alzheimer's patients, disrupt many brain functions and can kill neurons. They can also damage the blood-brain barrier—the normally tight border that ...

Medications

Potential drug targets for ALS and FTD identified in two studies

A pair of collaborative studies led by Fen-Biao Gao, Ph.D., have identified two potential drug targets for the diseases amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). The studies, which appear in Nature ...

Neuroscience

Serotonin boosts neuronal powerplants protecting against stress

Mitochondria in neurons are the powerhouses that generate energy to execute cellular functions and regulate neuronal survival under conditions of stress. Collaborative research by Prof. Vidita Vaidya and Prof. Ullas Kolthur-Seetharam ...

Neuroscience

The GPS of neurons now better understood

Our nerves consist of small cables responsible for circulating information to every part of our body, allowing us, for instance, to move. These cables are actually cells called neurons with long extensions named axons.

Neuroscience

Growing a cerebral tract in a microscale brain model

An international research team led by The University of Tokyo modeled the growth of cerebral tracts. Using neurons derived from stem cells, they grew cortical-like spheroids. In a microdevice, the spheroids extended bundles ...

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