In neuromuscular diseases, neurons and muscle cells stop communicating properly. Researchers led by Mina Gouti can now model this in 2D in a culture dish. Writing about their findings in Nature Communications, they say the ...
Dec 19, 2023
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A so-called pathological protein long associated with Parkinson's disease has been found in a new study to trigger cells to increase protein synthesis, an event that eventually kills the subset of brain cells that die off ...
Dec 18, 2023
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In a first-of-its-kind study published in Nature, researchers in the lab of Edward Chang, MD, at the University of California, San Francisco (UCSF) recorded activity from hundreds of individual neurons while participants ...
Dec 14, 2023
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Spinal cord stimulation can elicit sensation in the missing foot and alleviate phantom limb pain in people with lower limb amputations, University of Pittsburgh School of Medicine rehabilitation scientists report today.
Dec 14, 2023
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New research reveals that neurons in the preoptic hypothalamus—the region of the brain that regulates sleep and body temperature—are rhythmically activated during non-rapid eye movement sleep (NREM). Stress activates ...
Dec 13, 2023
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An established transcription factor known for bone formation also supports specialized cells in the central nervous system to promote brain tissue stiffness, findings that could inform new therapeutics for neuronal regeneration, ...
Dec 12, 2023
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When brain oxygenation is cut off for a prolonged period, the electrical activity of the cerebral cortex is quickly reduced to zero. But that's not the end of the story.
Dec 12, 2023
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Humans and other mammals can produce a wide range of sounds, while also modulating their volume and pitch. These sounds, also known as mammalian vocalizations, play a central role in communication between both animals of ...
Spinal muscular atrophy (SMA) is a devastating pediatric neuromuscular disorder caused by loss-of-function mutations in the SMN1 gene, which prevents the body from producing enough of the survival motor neuron (SMN) protein ...
Dec 7, 2023
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Animals and humans follow specific daily patterns known as circadian rhythms, which naturally prompt their bodies to sleep, wake up, eat and have other physiological responses at specific times. The disruption of these rhythms ...
