Diseases, Conditions, Syndromes

Understanding neutropenia

Q: My 1-year-old has neutropenia, and his neutrophil count is very low (310). He often gets infections, and his neutrophil count goes even lower when he's on antibiotics. What are our options at this point to get him healthy?

Oncology & Cancer

Chemo combination promising for multiple myeloma

(HealthDay) -- For patients with relapsed or refractory multiple myeloma, combination treatment with elotuzumab, lenalidomide, and low-dose dexamethasone is generally well tolerated, with encouraging response rates, according ...

Oncology & Cancer

Rituximab plus lenalidomide effective in follicular lymphoma

(HealthDay)—Rituximab plus lenalidomide has similar efficacy to rituximab plus chemotherapy among patients with previously untreated follicular lymphoma, according to a study published in the Sept. 6 issue of the New England ...

Medications

New drug approved for lack of certain white blood cells

(HealthDay)—The U.S. Food and Drug Administration has approved the drug tbo-filgrastim to treat certain cancer patients undergoing chemotherapy who have a condition called severe neutropenia, the FDA said in a news release.

Medical research

Mathematical model may lead to safer chemotherapy

Cancer chemotherapy can be a life-saver, but it is fraught with severe side effects, among them an increased risk of infection. Until now, the major criterion for assessing this risk has been the blood cell count: if the ...

Genetics

Mutation disables innate immune system

A Ludwig Maximilian University of Munich team has shown that defects in the JAGN1 gene inhibit the function of a specific type of white blood cells, and account for a rare congenital immune deficiency that increases vulnerability ...

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