Owing to a rare genetic mutation, individuals with leukocyte adhesion deficiency type 1 (LAD1) experience a suite of symptoms that trace back to an immune system dysfunction. Many have recurrent bacterial infections and gum ...
May 27, 2020
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Although advances in genetics and genomics reveal numerous disease-associated gene mutations associated with disease, physicians and researchers still wrestle with the tricky challenge of linking those mutations to actual ...
Apr 22, 2020
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Scientists at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) have discovered a 'disarmament' mechanism that protects against the uncontrolled activity of the immune system. This newly identified immune control ...
Jan 13, 2020
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For many lung cancer patients, the best treatment options involve checkpoint inhibitors. These drugs unleash a patient's immune system against their disease and can yield dramatic results, even in advanced cancers.
Dec 20, 2019
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When the immune system detects a foreign pathogen, a cascade of chemical signals call white blood cells to the scene. Neutrophils are the most common and abundant type of these cells and while they start accumulating at the ...
Dec 13, 2019
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A study led by researchers at Washington State University has uncovered a potential new treatment approach for diseases associated with inflammation, including sepsis, stroke, rheumatoid arthritis, acute lung injury, and ...
Nov 6, 2019
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Malaria is one of the world's deadliest infectious diseases: a small mosquito bite delivers numerous malaria parasites into the bloodstream. The human body defends itself valiantly against the parasite, which usually results ...
Oct 21, 2019
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In recent decades, asthma has become a major public health problem. The exponential increase in asthma cases in industrialized countries over the past 50 years is due to major changes in the environment. Among these environmental ...
Oct 7, 2019
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Medications that mitigate inflammation caused by a variety of diseases including rheumatic arthritis may also compromise a person's immune system, but a new approach points to a possible solution to this problem.
Sep 16, 2019
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In recent years it has been increasingly appreciated that immune cells within the tumor microenvironment contribute to tumor progression and, importantly, to the tumor's response to therapy. To better understand the specific ...
Aug 26, 2019
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