Oncology & Cancer

Expression of specific gene differentiates moles from melanoma

Most melanomas are driven by mutations that spur out-of-control cell replication, while nevi (moles composed of non-cancerous cells at the skin surface) harboring the same mutations do not grow wildly. However, changes in ...

Oncology & Cancer

Dermoscopically, melanoma, spitz nevi indistinguishable

(HealthDay)—Melanoma may be dermoscopically indistinguishable from Spitz nevi, according to a study published in the January issue of the Journal of the American Academy of Dermatology.

Oncology & Cancer

Moles linked to risk for breast cancer

Cutaneous nevi, commonly known as moles, may be a novel predictor of breast cancer, according to two studies published in this week's PLOS Medicine. Jiali Han and colleagues from Indiana University and Harvard University, ...

Diseases, Conditions, Syndromes

Moderately dysplastic nevi re-excision not necessary

(HealthDay)—Re-excision of mildly or moderately histologically dysplastic nevi (HDN) that approach a microscopic border may not be necessary, as favorable long-term outcomes are achieved without re-excision, according to ...

Oncology & Cancer

Polyclonality of BRAF mutations in acquired melanocytic nevi

The polyclonality of BRAF mutations in melanocytic nevi suggests that mutation of BRAF may not be an initial event in melanocyte transformation, according to a new brief communication published online September 14 in the ...

Oncology & Cancer

Beach vacations may increase future skin cancer risk in children

Vacationing at the shore led to a 5 percent increase in nevi (more commonly called "moles") among 7-year-old children, according to a paper published in Cancer Epidemiology, Biomarkers and Prevention, a journal of the American ...