In 1998, when Timothy Hla, Ph.D., and his colleagues identified and cloned the receptor for sphingosine-1-phosphate (S1P), it generated a lot of excitement. S1P, a lipid originally discovered in the 1960s, was known to play ...
Mar 11, 2020
0
79
St. Jude Children's Research Hospital scientists have discovered a gene associated with about half of glucocorticoid resistance in children with the most common pediatric cancer. Researchers have also identified a drug that ...
Mar 9, 2020
0
101
The number of people infected with the new coronavirus continues to skyrocket, with more than 80,000 cases worldwide as of the end of February. But there's no vaccine or cure in sight, meaning that doctors can do little more ...
Feb 27, 2020
1
321
A molecule identified by UCLA researchers helps maintain a healthy balance of cells in airway and lung tissue. If the compound, so far only studied in isolated human and mouse cells, has the same effect in people, it may ...
Feb 19, 2020
0
340
A tiny molecule of RNA—known as 'micro RNA' - plays a key role in 'rewiring' cancer cells so they can resist the effects of chemotherapy, a new study reveals.
Feb 12, 2020
0
88
Drug development is an extremely arduous and costly process, and failure rates in clinical trials that test new drugs for their safety and efficacy in humans remain very high. According to current estimates, only 13.8% of ...
Jan 27, 2020
0
251
Autoimmune disorders such as rheumatoid arthritis, psoriasis, and Crohn's disease plague tens of millions of Americans and are the result of the body's immune system, whose role is to fight against disease-causing pathogens, ...
Dec 12, 2019
0
57
A common first-line treatment approach for cryptococcal meningitis in low-income countries is being compromised by the emergence of drug resistance, new University of Liverpool research warns.
Dec 6, 2019
0
88
Scientists at the University of Virginia School of Medicine have developed a better way to determine what our genes do, allowing scientists to better probe the genetic causes of diseases and more efficiently determine whether ...
Nov 8, 2019
0
54
An international research team has developed a new strategy that can predict the potential clinical implications of new therapeutic compounds based on simple cellular responses. This discovery was partly led by scientists ...
Sep 13, 2019
0
39
