Cardiology

Listening to favorite music improves endothelial function in CAD

Listening to favorite music improves endothelial function in patients with coronary artery disease, according to research presented at ESC Congress 2013 today by professor Marina Deljanin Ilic from Serbia. Music and exercise ...

Medical research

Fountain of youth for heart health may lie in the gut

Why do blood vessels naturally stiffen and degrade as we age, boosting cardiovascular disease risk? New University of Colorado Boulder research has identified a surprising new culprit—and it lives in your gut.

Diseases, Conditions, Syndromes

Study finds new pathways to treat non-alcoholic fatty-liver disease

Researchers from the University of South Carolina, Duke University, University of Alabama at Birmingham, and Metabolon Inc. Research Triangle Park have discovered a new pathway in the liver that opens the door to treat non-alcoholic ...

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Nitric oxide

Nitric oxide or nitrogen monoxide is a chemical compound with chemical formula NO. This gas is an important signaling molecule in the body of mammals, including humans, and is an extremely important intermediate in the chemical industry. It is also an air pollutant produced by cigarette smoke, automobile engines and power plants.

NO is an important messenger molecule involved in many physiological and pathological processes within the mammalian body both beneficial and detrimental. Appropriate levels of NO production are important in protecting an organ such as the liver from ischemic damage. However sustained levels of NO production result in direct tissue toxicity and contribute to the vascular collapse associated with septic shock, whereas chronic expression of NO is associated with various carcinomas and inflammatory conditions including juvenile diabetes, multiple sclerosis, arthritis and ulcerative colitis.

Nitric oxide should not be confused with nitrous oxide (N2O), a general anaesthetic and greenhouse gas, or with nitrogen dioxide (NO2) which is another air pollutant. The nitric oxide molecule is a free radical, which is relevant to understanding its high reactivity.

Despite being a simple molecule, NO is a fundamental player in the fields of neuroscience, physiology, and immunology, and was proclaimed “Molecule of the Year” in 1992.

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