Medications

Popular painkiller ibuprofen affects liver enzymes in mice

The popular painkiller ibuprofen may have more significant effects on the liver than previously thought, according to new research from the University of California, Davis. The study in laboratory mice also shows marked differences ...

Genetics

Long noncoding RNA identified as a key regulator of inflammation

Scientists have identified an RNA molecule with broad powers to regulate the body's inflammatory response to infection and injury. Called lincRNA-Cox2, it belongs to a recently discovered, highly abundant class of RNAs whose ...

Oncology & Cancer

Gut microbiome may make chemo drug toxic to patients

Albert Einstein College of Medicine researchers report that the composition of people's gut bacteria may explain why some of them suffer life-threatening reactions after taking a key drug for treating metastatic colorectal ...

Genetics

Researchers explore epigenetic influences of chronic pain

Chronic pain is one of the most prevalent, disabling and expensive public health crises in the United States. It affects more than 100 million Americans, with annual costs estimated at $635 billion, says a 2014 report from ...

Neuroscience

Opioids provide low evidence of pain relief for migraine

Evidence that opioids provide pain relief for migraine headaches is low or insufficient, a large Mayo Clinic meta-analysis published recently in JAMA has found. However, some newer therapies, along with established migraine ...

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