Genetics

Moving a cardiac regulatory protein to the right place

The largest known protein, titin, named for the Titan giants of Greek mythology, is a molecular spring found in cardiac muscle. It provides structural support and maintains tension during muscle stretching. Mutations in the ...

Neuroscience

Research reveals atomic-level changes in ALS-linked protein

For the first time, researchers have described atom-by-atom changes in a family of proteins linked to amyotrophic lateral sclerosis (ALS), a group of brain disorders known as frontotemporal dementia and degenerative diseases ...

Genetics

Multifunctional protein contributes to blood cell development

Like an actor who excels at both comedy and drama, proteins also can play multiple roles. Uncovering these varied talents can teach researchers more about the inner workings of cells. It also can yield new discoveries about ...

Medical research

Tackling infectious disease – one protein at a time

Garry Buchko and his colleagues are at the front line battling some of the most fearsome enemies that humanity has ever known: Tuberculosis. Pneumonia. Ebola. Plague. Botulism.

Alzheimer's disease & dementia

Behavior of Alzheimer's-linked protein is revealed

Enzymes called kinases manage a wide range of cell processes, from metabolism, cell signaling, nutrient transport, and many others. Because they can affect so many different cell activities, kinases are tightly regulated ...

page 2 from 5