Oncology & Cancer

New insights into melanoma development and therapy

Malignant melanoma is a type of skin cancer that originates from melanocytes or nevi, causing about 80% of skin cancer-related deaths. While some cases have shown significant response to existing molecular targeted therapies, ...

Endocrinology & Metabolism

Metabolism meets signaling to fine-tune cell growth

Cells use a variety of metabolic pathways to synthesize the building blocks for growth and proliferation. To ensure balanced growth, these biosynthetic processes must be tightly coordinated. Researchers from the Max Planck ...

Diseases, Conditions, Syndromes

Know your status: The importance of HIV testing

It's not making major news headlines like in the '80s, but HIV remains a significant health concern. About 38 million people are living with HIV, the virus that causes AIDS, according to the World Health Organization.

Medical research

Calcium: A key player for a promising and safe brain treatment?

A promising therapy for a range of brain diseases involves antisense oligonucleotides (ASOs)—specialized molecules that can modulate RNA and alter protein production—directly injected into the cerebrospinal fluid, in ...

Medical research

Terminal sterilization of oligonucleotide drug products

A new report, coauthored by several major pharmaceutical companies, reviews the current state of sterile oligonucleotide drug product processing. The article, which provides recommendations to aid in the evaluation and development ...

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