Genetics

DNA tests make fun holiday gifts, but beware of the hype

You've likely heard about direct-to-consumer DNA testing kits. In the past few years, at-home genetic testing has been featured in the lyrics of chart-topping songs, and has helped police solve decades-old cold cases, including ...

Oncology & Cancer

'Junk DNA' affects inherited cancer risk

A person's risk of developing cancer is affected by genetic variations in regions of DNA that don't code for proteins, previously dismissed as 'junk DNA', according to new research published in the British Journal of Cancer ...

Oncology & Cancer

New screening method identifies inhibitors of cancer cell metabolism

A new screening system developed by scientists at the UCLA Jonsson Comprehensive Cancer Center leverages redundancy in an important component of a cell—nucleotide metabolism—to help identify new drugs that specifically ...

Medical research

New study challenges our understanding of premature ageing

Disturbances in the function of mitochondrial DNA can accelerate the ageing process in ways that are different than previously thought, according to a new Finnish study published in Nature Metabolism. Offering a new perspective ...

Medical research

Cancer's SOS

RAS proteins regulate growth, survival and proliferation of cells in their active state. However, the uncontrolled activation of RAS causes approximately a third of all tumors and helps cancerous cells evade anti-cancer drugs. ...

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Nucleotide

Nucleotides are molecules that, when joined together, make up the structural units of RNA and DNA. In addition, nucleotides participate in cellular signaling (cGMP and cAMP), and are incorporated into important cofactors of enzymatic reactions (coenzyme A, FAD, FMN, and NADP+). Nucleotide derivatives such as the nucleoside triphosphates play central roles in metabolism, in which capacity they serve as sources of chemical energy (ATP and GTP).

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