Cutting-edge sequencing technology has revolutionized cancer diagnosis and since identified several so-called cancer driver genomic aberrations. This has led to the development of an extensive and powerful arsenal of anti-cancer ...
Mar 20, 2019
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Inside cells DNA is tightly wrapped around proteins and packed in a complex, 3-D structure called chromatin. Chromatin not only protects genetic material from damage, but also organizes the entire genome by regulating the ...
Jan 29, 2019
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Glioblastoma (GBM) is the most common and aggressive form of brain cancer. Response to standard-of-care treatment is poor, with a two-year survival rate of only 15 percent. Research is beginning to provide a better understanding ...
Apr 23, 2018
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By the time Ewing's Sarcoma is diagnosed, primarily in teens and young adults, it has often spread from its primary site to other parts of the body, making it difficult to treat. A University of Colorado Cancer Center study ...
Mar 24, 2017
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In a finding with enormous implications for cancer diagnostics and therapeutics, Whitehead Institute scientists have discovered that breaches in looping chromosomal structures known as "insulated neighborhoods" can activate ...
Mar 3, 2016
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An interdisciplinary team of chemists, oncologists and one statistician at Stanford has taken the first step toward developing a technique that can identify the origin of certain types of cancer—a potential boon to doctors ...
Jul 11, 2014
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For more than 100 years, researchers have been unable to explain why cancer cells contain abnormal numbers of chromosomes, a phenomenon known as aneuploidy. Many believed aneuploidy was simply a random byproduct of cancer.
Oct 31, 2013
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Scanning the DNA of nearly 5,000 tumor samples, a team led by scientists at Dana-Farber Cancer Institute and the Broad Institute has identified 140 regions of scrambled genetic code believed to contain many undiscovered cancer ...
Sep 27, 2013
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Two Houston researchers from Baylor College of Medicine and Texas Children's Hospital were part of an international team that developed a new gene therapy approach to treatment of Wiskott-Aldrich Syndrome, a fatal inherited ...
Jul 11, 2013
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Scientists at The Scripps Research Institute (TSRI) have identified key triggers of an important cancer-blocking mechanism in cells.
Jun 11, 2013
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