Cancer treatment can rob childbearing-age women of fertility, but new research has uncloaked how the body's own traitor protein conspires with chemo and other harsh therapies against the ovaries' primordial follicles, home ...
For the first time, Massachusetts General Hospital (MGH) researchers have isolated egg-producing stem cells from the ovaries of reproductive age women and shown these cells can produce what appear to be normal egg cells or ...
Feb 26, 2012
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VUB professor Claudia Spits, of the Vrije Universiteit Brussel Reproduction and Genetics research group, has identified a genetic cause for the increased risk of low birth weight in babies born following assisted reproductive ...
Feb 12, 2024
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A team of reproductive biologists at Nanjing Agricultural University has found that spermidine, a polyamine metabolite, helps oocytes clear away damaged mitochondria in mice, thereby improving mitophagy during female reproductive ...
A team of researchers with several members affiliated with Kyoto University and one with Tokyo Medical and Dental University has found a way to restore fertility to mice models with granulosa communication problems. In their ...
Inheriting a normal and intact number of chromosomes in germ cells, egg and sperm, is essential for the preservation of all species. With increasing age, the risk of the egg cell not inheriting the normal set of chromosomes ...
Feb 4, 2022
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Researchers led by Kyushu University have succeeded in using mouse stem cells to reconstruct structures in the ovarian environment critical for the generation of mature egg cells. Moreover, they were able to apply their findings ...
Sep 14, 2021
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Age may adversely affect women's fertility by impairing levels of RNA molecules which in turn alter the function of genes involved in key biological pathways during the final maturation stage of a human egg cell, according ...
Apr 28, 2021
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More than 7% of human oocytes contain at least one exchangeless chromosome pair, demonstrating a remarkably high level of meiotic recombination failure, finds a study appearing December 10 in the American Journal of Human ...
Dec 10, 2020
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A Monash University study has uncovered the role DNA repair plays in preserving egg quality, offering hope for women whose eggs may be damaged through treatments such as radiation and chemotherapy.
May 22, 2020
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An oocyte, ovocyte, or rarely ocyte, is a female gametocyte or germ cell involved in reproduction. In other words, it is an immature ovum, or egg cell. An oocyte is produced in the ovary during female gametogenesis. The female germ cells produce a primordial germ cell (PGC) which undergoes a mitotic division to form an oogonium. During oogenesis the oogonium becomes a primary oocyte (pronounced oh'a-site).
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