There is an urgent need to identify reliable predictors of opioid responses to develop personalized opioid therapy for chronic pain management. A goal is to target opioid therapy to patients most likely to benefit from treatment ...
Mar 1, 2019
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Tobacco is a known risk factor for the misuse of prescription opioids. In addition, concurrent use of opioids and sedative-hypnotics is a risk factor for opioid overdose or addiction.
Jan 10, 2019
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What does a marine snail's ability to kill prey with two shots of venom have to do with the opioid epidemic ravaging the United States?
Nov 28, 2017
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COVID-19 has been associated with increases in opioid overdose deaths, which may be in part because the pandemic limited access to buprenorphine, a treatment used for opioid dependency, according to a new study led by Princeton ...
Apr 15, 2021
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In the wake of an opioid-related event such as an overdose, infection, or detox admission, white patients received medication for opioid use disorder (OUD) up to 80% more frequently than Black patients and up to 25% more ...
May 10, 2023
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The treatment of inflammatory pain can be improved by endogenous opioid peptides acting directly in injured tissue. Scientists at the Charité – Universitätsmedizin Berlin and the Université Paris Descartes showed that ...
Dec 4, 2012
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(HealthDay)—The use of opioid analgesics may increase the risk of serious infection in patients with rheumatoid arthritis (RA), according to research published in the February issue of Arthritis & Rheumatology.
Feb 15, 2016
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Opioid analgesics, or prescription-based narcotic pain killers, have long been known to reduce pain, but reports of adverse effects and addiction continue to surface. Now, a team of investigators led by a Saint Louis University ...
Oct 31, 2013
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The most powerful analgesic and addictive properties of opiate alkaloids are mediated by the m-opioid receptor (mOR). As the receptor primarily responsible for the effects of opium, the mOR is one of the oldest drug targets ...
Aug 6, 2015
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A new study describes trends in filled opioid prescriptions by patient and clinical characteristics for Medicaid-enrolled children. Findings from the study will be presented during the Pediatric Academic Societies (PAS) 2019 ...
Apr 27, 2019
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